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Harvard Medical School
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General Medical Questions
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Q: I had a bubble of fluid on the back side of my eyeball. After 6 weeks, it’s re-absorbed. But now I need a test called fluorescein angiogram, where they inject yellow dye into my eye to look for CSR. What is CSR — and what are the risks?
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The Trusted Source
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Don Carl Bienfang, M.D, is an assistant professor of ophthalmology at Harvard Medical School and the director of neuro-ophthalmology and senior surgeon of the Department of Ophthalmology at Brigham and Women's Hospital.

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January 20, 2012
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A:

CSR stands for Central Serous Retinopathy. It is a condition in where fluid from the blood vessels behind the retina leaks under the retina and lifts it slightly up. It’s typically temporary. And why it happens is unknown.

In almost all cases, it happens in the early adult years and heals spontaneously. It often comes with emotional stress.

CSR poses no risks, unless it doesn’t go away. Vision changes — even during the active phase of the blister — are minimal.

If the condition persists, LASER can seal the small hole in the barrier between the retina and these blood vessels.

Sometimes people think that fluorescein angiography involves an injection in the eye. It doesn’t. The dye is injected into a vein. The dye circulates through the blood stream and into the blood vessels of the eyes. Then, a rapid sequence of photographs of the retina is taken to look for the leaking hole. As long as you are not allergic to the dye, this is a safe study.

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